김윤균 사진

김윤균 | 약학대학 약학과

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    교수

학력

  • [1994] 학사 서울대학교 약학
  • [1997] 석사 서울대학교 약물학 약리학
  • [2001] 박사 서울대학교 약물역학 약리학

주요연구분야

Clincal Pharmacology
Pharmacometrics (PK-PD modeling & simulation)

연구업적

  • 연구보고서[20060401] '레보론정'(Levosulpiride, 25 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20060301] '다코나졸캡슐'(Fluconazole, 50 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20060301] "온스나졸캡슐 (Fluconazole, 50 mg)"의 생물학적동등성시험 결과보고서
  • 연구보고서[20060201] "말레인산암로디핀정 5 mg (Amlodipine maleate 6.4mg)"의 생물학적동등성시험 결과보고서
  • 연구보고서[20060201] '스파졸캡슐'(Itraconazole, 100 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20060201] '레카핀정'(Lercanidipine HCl, 10mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20060101] "염산레르카니디핀정(Lercanidipine HCl 10mg)"의 생물학적동등성시험 결과보고서
  • 연구보고서[20051201] '말레인산암로디핀정 5mg'(Amlodipine maleate, 6.4 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20051101] "칼딥정 (Lercanidipine HCl, 10mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20051101] '엘카론정'(acetyl-L-carnitine, 500 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20051101] "디로칸캡슐" (Fluconazole, 50 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20051101] "가바펜틴캡슐 300mg (Gabapentin 300mg)"의 생물학적동등성시험 결과보고서
  • 연구보고서[20050901] "로자탄칼륨정 (Losartan potassium, 50 mg)"의 생물학적동등성시험 결과보고서
  • 연구보고서[20050901] '피나스테리드정'(finasteride, 5 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050901] '로자탄칼륨정’ (losartan otassium, 50 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050801] '드림파마 시메티딘정'(cimetidine, 400 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050801] "위더스페낙정(아세클로페낙)"의 생물학적동등성시험 결과 보고서
  • 연구보고서[20050701] "디로칸캡슐" (Fluconazole, 50 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050701] "디크리핀지속정 (Felodipine, 5 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050601] '아디핀정'(Felodipine, 5 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050601] "아세라제캡슐 (Acebrophylline, 100mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050501] '대웅가바펜틴정'(gabapentin, 600 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050501] "이연프로피베린정 (Propiverine HCl, 20mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050401] '벤팍신OR서방정75mg'(venlafaxine, 75 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050401] '셀렉틴캡슐'(fluoxetine, 20 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050401] '스파졸캡슐'(Itraconzole, 100mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050401] '광동펠로디핀지속정'(Felodipine, 5 mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050301] 한국콜마말레인산트리메부틴정 (Trimebutine maleate, 100mg)의 생물학적동등성시험 결과보고서
  • 연구보고서[20050201] '가바렙캡슐300mg'(gabapentin, 300 mg)의 생물학적동등성시험 결과보고서
  • 일반논문[20131001] Antiplatelet effect of AMP-activated protein kinase activator and its potentiation by the phosphodiesterase inhibitor dipyridamole
  • 일반논문[20130901] Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of ε-Acetamidocaproic Acid in Rat Plasma
  • 일반논문[20130201] Protective effect of nectandrin B, a potent AMPK activator on neointima formation: inhibition of Pin1 expression through AMPK activation
  • 일반논문[20121101] DEVELOPMENT OF A LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY METHOD FOR THE DETERMINATION OF INDIRUBIN-5-NITRO-3 '-MONOXIME, A NOVEL CDK INHIBITOR, IN RAT PLASMA
  • 일반논문[20120801] Enhancement of solubility and dissolution rate of cryptotanshinone, tanshinone I and tanshinone IIA extracted from Salvia miltiorrhiza
  • 일반논문[20120501] Effects of cysteine on the pharmacokinetics of docetaxel in rats with protein-calorie malnutrition
  • 일반논문[20120301] Acetamidocaproic acid pharmacokinetics in rats with gastric ulcer or small bowel inflammation.
  • 일반논문[20111101] Application of Drug Metabolism and Pharmacokinetics for New Drug Development PREFACE
  • 일반논문[20111101] Herb-Drug Interactions: Focus on Metabolic Enzymes and Transporters
  • 일반논문[20110901] Effect of genetic polymorphisms on the pharmacokinetics and efficacy of glimepiride in a Korean population
  • 일반논문[20110601] A comparative study of the pharmacokinetics of traditional and automated dosing/blood sampling systems using gabapentin
  • 일반논문[20110501] Pharmacokinetic interaction between epsilon-acetamidocaproic acid (AACA) and cimetidine in indomethacin-induced acute gastric ulcer and control rats: inhibition of active renal secretion of AACA by cimetidine
  • 일반논문[20101101] Amurensin G, a Potent Natural SIRT1 Inhibitor, Rescues Doxorubicin Responsiveness via Down-Regulation of Multidrug Resistance 1
  • 일반논문[20101001] Resolvin D1 attenuates activation of sensory transient receptor potential channels leading to multiple anti-nociception
  • 일반논문[20100701] Pharmacokinetics and first-pass effects of epsilon-acetamidocaproic acid after administration of zinc acexamate in rats
  • 일반논문[20091230] 단국대학교 약학대학의 역할: 단국대학교 의약바이오클러스터의 발전 및 충남 보건약료전문가의 양성
  • 일반논문[20090701] A fully validated HPLC method for the simultaneous determination of acitretin and etretinate in plasma and its application to a pharmacokinetic study in healthy Korean subjects
  • 일반논문[20090401] Pharmacokinetics of Amitriptyline and One of Its Metabolites, Nortriptyline, in Rats: Little Contribution of Considerable Hepatic First-Pass Effect to Low Bioavailability of Amitriptyline Due to Great Intestinal First-Pass Effect
  • 일반논문[20081201] Bioequivalence Studies of Tibolone in Premenopausal Women and Effects on Expression of the Tibolone-Metabolizing Enzyme AKR1C (Aldo-Keto Reductase) Family Caused by Estradiol
  • 일반논문[20081101] Evaluation of the transfusion safety of blood products and determination of plasma concentrations of acitretin and etretinate in patients receiving transfusions
  • 일반논문[20080221] 트리테이스프로텍트®정(라미프릴 10 mg)에 대한 라미프린®정의 생물학적동등성
  • 일반논문[20071221] 이팩사®XR서방캅셀(벤라팍신, 75 mg)에 대한 벤팍신®OR서방정의 생물학적동등성
  • 일반논문[20071101] Transient receptor potential A1 mediates acetaldehyde-evoked pain sensation.
  • 일반논문[20071021] Bioequivalence of Samchundang Lercanidipine Tablet 10 mg to Zanidip Tablet (Lercanidipine Hydrochloride 10 mg) by Liquid Chromatography with Tandem Mass Spectrometry
  • 일반논문[20070821] 염산레르카니디핀 체내동태 연구를 위한 혈청 중 레르카니디핀의 LC/MS/MS 정량법 검증
  • 일반논문[20070630] Effects of R. Glutinosa and E. Senticosus on postmenopausal osteroporesis.
  • 일반논문[20070301] 7,7'-Dihydroxy bursehernin inhibits the expression of inducible nitric oxide synthase through NF-kappaB DNA binding suppression.
  • 일반논문[20060821] 제스트릴정(리시노프릴, 10 mg)에 대한 리시헥살정의 생물학적동등성
  • 일반논문[20060801] Antioxidative effects of quercetin-glycosides isolated from the flower buds of Tussilago farfara L
  • 일반논문[20060801] Pharmacokinetic parameters of bromperidol in Korean subjects
  • 일반논문[20060724] Pharmacokinetic study of orphenadrine using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)
  • 일반논문[20051221] 테르페나딘 체내동태 연구를 위한 혈청 중 펙소페나딘의 HPLC 정량법 개발 및 검증
  • 일반논문[20051221] 페노프로펜 체내동태 연구를 위한 혈청 중 페노프로펜의 HPLC 정량법 개발 및 검증
  • 일반논문[20051201] Chrysoeriol potently inhibits the induction of nitric oxide synthase by blocking AP-1 activation
  • 일반논문[20050701] Effects of phenylethanoid glycosides from Digitalis purpurea L. on the expression of inducible nitric oxide synthase.
  • 일반논문[20050701] Interspecies pharmacokinetic scaling of DA-8159, a new erectogenic, in mice, rats, rabbits, and dogs, and prediction of human pharmacokinetics
  • 일반논문[20050303] Hepatic and intestinal first-pass effects of oltipraz in rats
  • 일반논문[20050201] Interspecies pharmacokinetic scaling of oltipraz in mice, rats, rabbits and dogs, and prediction of human pharmacokinetics
  • 일반논문[20041130] LC-ESI-MS/MS를 이용한 생체시료 중 브롬화피나베리움의 고감도 분석 및 이를 이용한 생체이용률 평가
  • 일반논문[20040901] Bioequivalence of a prednisolone tablet administered as a single oral dose in healthy male volunteers
  • 일반논문[20040501] Bioequivalence of pravastatin tablet formulations assessed in Korean males
  • 일반논문[20040101] Bioequivalence assessment of ambroxol tablet after a single oral dose administration to healthy male volunteers.
  • 일반논문[20031201] Comparative bioavailability of silibinin in healthy male volunteers
  • 일반논문[20031103] Bioequivalence study of two erdosteine capsule formulations in healthy male volunteers
  • 일반논문[20030801] Dose-independent pharmacokinetics of a new reversible proton pump inhibitor, KR-60436, after intravenous and oral administration to rats: Gastrointestinal first-pass effect.
  • 일반논문[20030601] High-performance liquid chromatographic analysis of nitrendipine in human plasma using ultraviolet detection and single-step solid-phase sample preparation
  • 일반논문[20030501] Dose-independent pharmacokinetics of a candidate for diabetic neuropathy, SR-4668, after intravenous and oral administration to rats: Intestinal first-pass effect
  • 일반논문[20030401] Effects of cysteine on the pharmacokinetics of intravenous 2-(allylthio)pyrazine, a new chemoprotective agent, in rats with protein-calorie malnutrition
  • 일반논문[20030301] Pharmacokinetics of intravenous chlorzoxazone in rats with dehydration and rehydration: effects of food intakes.
  • 일반논문[20030101] Dose-independent pharmacokinetics of a new neuroprotective agent for ischemia-reperfusion damage, KR-31543, after intravenous and oral administration to rats: Hepatic and intestinal first-pass effects
  • 일반논문[20030101] Effects of cysteine on amino acid concentrations and transsulfuration enzyme activities in rat liver with protein-calorie malnutrition
  • 저서/역서[20060125] Katzung 약리학
  • 저서/역서[20050901] 하버드핵심약리학(약물요법의 병태생리학적 기초)
  • 저서/역서[20050825] 임상약리학4
  • 학술발표[20071112] Bioavailability of two clopidogrel formulations in healthy male volunteers; comparison between clopidogrel and its metabolite carboxyl clopidogrel as pharmacokinetic parameter.
  • 학술발표[20071107] Pharmacokinetic interaction between DA-8159 (Zydena®) and tamsulosin in rats: Inhibition of tamsulosin metabolism by DA-8159 primarily via hepatic CYP3A1/2.
  • 학술발표[20061116] Pharmacokintecs of phenolic acid, iridoid glycoside and flavonoids in rats following oral administration of multi-herbs formula Hyungga-Yeongyo Tang
  • 학술발표[20061116] Pharmacokinetic characteristics of mazindol in healthy male Korean volunteers
  • 학술발표[20061116] Combined in vivo microdialysis and intragastric catheter administration for the determination of brain venlafaxine metabolism in freely-moving mice
  • 학술발표[20061106] Comparative bioavailability of two clopidogrel formulations in healthy male volunteers; Comparison between clopidogrel and its metabolite carboxyl clopidogrel as pharmacokinetic parameters
  • 학술발표[20051128] Pharmacokinetics of gabapentin in rat with acute renal failure induced by uranyl nitrate
  • 학술발표[20051128] Qualitative estimation of major constituents of Sopung-San using UV-fingerprint ans ESI-LC-MS-MS
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