이충현 사진

이충현 | 약학대학 약학과

  • 직급:
    부교수

학력

  • [2000] 학사 서울대학교 수의학과(수의학) 수의학
  • [2002] 석사 서울대학교 수의학과 신경해부학
  • [2008] 박사 서울대학교 수의학과 신경해부학

주요연구분야

노화에 따른 뇌 안에서의 변화
신경세포 손상 및 보호

연구업적

  • 일반논문[20190601] Pretreatment of Populus tomentiglandulosa protects hippocampal CA1 pyramidal neurons from ischemia-reperfusion injury in gerbils via increasing SODs expressions and maintaining BDNF and IGF-I expressions
  • 일반논문[20190301] Intermittent fasting increases the expressions of SODs and catalase in granule and polymorphic cells and enhances neuroblast dendrite complexity and maturation in the adult gerbil dentate gyrus
  • 일반논문[20190204] Decreased dopamine in striatum and difficult locomotor recovery from MPTP insult after exposure to radiofrequency electromagnetic fields
  • 일반논문[20181231] Melatonin improves vascular cognitive impairment induced by ischemic stroke by remyelination via activation of ERK1/2 signaling and restoration of glutamatergic synapses in the gerbil hippocampus
  • 일반논문[20181231] Chronic high-fat diet-induced obesity in gerbils increases pro-inflammatory cytokines and mTOR activation, and elicits neuronal death in the striatum following brief transient ischemia
  • 일반논문[20181130] Time-Course Changes and New Expressions of MIP-3 and Its Receptor, CCR6, in the Gerbil Hippocampal CA1 Area Following Transient Global Cerebral Ischemia
  • 일반논문[20180801] Melatonin Improves Cognitive Deficits via Restoration of Cholinergic Dysfunction in a Mouse Model of Scopolamine-Induced Amnesia
  • 일반논문[20180701] Early IV-injected human dermis-derived mesenchymal stem cells after transient global cerebral ischemia do not pass through damaged blood-brain barrier
  • 일반논문[20180701] Effect of Rufinamide on the kainic acid-induced excitotoxic neuronal death in the mouse hippocampus
  • 일반논문[20180601] Age-dependent decrease of Nurr1 protein expression in the gerbil hippocampus
  • 일반논문[20180401] Melatonin attenuates scopolamine-induced cognitive impairment via protecting against demyelination through BDNF-TrkB signaling in the mouse dentate gyrus
  • 일반논문[20180401] Rufinamide, an antiepileptic drug, improves cognition and increases neurogenesis in the aged gerbil hippocampal dentate gyrus via increasing expressions of IGF-1, IGF-1R and p-CREB
  • 일반논문[20180301] Long-term treadmill exercise improves memory impairment through restoration of decreased synaptic adhesion molecule 1/2/3 induced by transient cerebral ischemia in the aged gerbil hippocampus
  • 일반논문[20180301] Neuroprotective Effect of Duloxetine on Chronic Cerebral Hypoperfusion-Induced Hippocampal Neuronal Damage
  • 일반논문[20180301] Glehnia littoralis Extract Promotes Neurogenesis in the Hippocampal Dentate Gyrus of the Adult Mouse through Increasing Expressions of Brain-Derived Neurotrophic Factor and Tropomyosin-Related Kinase B
  • 일반논문[20180301] Age-dependent alteration in the expression of oligodendrocyte-specific protein in the gerbil hippocampus
  • 일반논문[20170901] Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils
  • 일반논문[20170701] Transient cerebral ischemia induces albumin expression in microglia only in the CA1 region of the gerbil hippocampus
  • 일반논문[20170601] Sac-1004, a vascular leakage blocker, reduces cerebral ischemia-reperfusion injury by suppressing blood-brain barrier disruption and inflammation
  • 일반논문[20170601] Atomoxetine Protects Against NMDA Receptor-mediated Hippocampal Neuronal Death Following Transient Global Cerebral Ischemia
  • 일반논문[20170401] Time-Course Change of Redd1 Expressions in the Hippocampal CA1 Region Following Chronic Cerebral Hypoperfusion
  • 일반논문[20170301] Temporal changes in mammalian target of rapamycin (mTOR) and phosphorylated-mTOR expressions in the hippocampal CA1 region of rat with vascular dementia
  • 일반논문[20170201] Pretreated quercetin protects gerbil hippocampal CA1 pyramidal neurons from transient cerebral ischemic injury by increasing the expression of antioxidant enzymes
  • 일반논문[20161201] Hydroquinone Strongly Alleviates Focal Ischemic Brain Injury via Blockage of Blood-Brain Barrier Disruption in Rats
  • 일반논문[20161101] Pretreated duloxetine protects hippocampal CA1 pyramidal neurons from ischemia-reperfusion injury through decreases of glial activation and oxidative stress
  • 일반논문[20161001] Age-dependent increase in the expression of antioxidant-like protein-1 in the gerbil hippocampus
  • 일반논문[20161001] Differential activation of c-Fos in the paraventricular nuclei of the hypothalamus and thalamus following myocardial infarction in rats
  • 일반논문[20161001] Long-Term Exercise Improves Memory Deficits via Restoration of Myelin and Microvessel Damage, and Enhancement of Neurogenesis in the Aged Gerbil Hippocampus After Ischemic Stroke
  • 일반논문[20160901] New GABAergic Neurogenesis in the Hippocampal CA1 Region of a Gerbil Model of Long-Term Survival after Transient Cerebral Ischemic Injury
  • 일반논문[20160801] Effects of Chronic Scopolamine Treatment on Cognitive Impairments and Myelin Basic Protein Expression in the Mouse Hippocampus
  • 일반논문[20160701] Comparison of catalase immunoreactivity in the hippocampus between young, adult and aged mice and rats
  • 일반논문[20160701] Ischemia-Induced Changes of PRAS40 and p-PRAS40 Immunoreactivities in the Gerbil Hippocampal CA1 Region After Transient Cerebral Ischemia
  • 일반논문[20160601] Effects of melatonin on cognitive impairment and hippocampal neuronal damage in a rat model of chronic cerebral hypoperfusion
  • 일반논문[20160601] Time-course changes of hippocalcin expression in the mouse hippocampus following pilocarpine-induced status epilepticus
  • 일반논문[20160301] Age-dependent changes in the protein expression levels of Redd1 and mTOR in the gerbil hippocampus during normal aging
  • 일반논문[20151201] Neuroprotection and reduced gliosis by atomoxetine pretreatment in a gerbil model of transient cerebral ischemia
  • 일반논문[20151201] Marmesin is a novel angiogenesis inhibitor: Regulatory effect and molecular mechanism on endothelial cell fate and angiogenesis
  • 일반논문[20151101] The anti-inflammatory activity of duloxetine, a serotonin/norepinephrine reuptake inhibitor, prevents kainic acid-induced hippocampal neuronal death in mice
  • 일반논문[20150801] Differences in the protein expression levels of Trx2 and Prx3 in the hippocampal CA1 region between adult and aged gerbils following transient global cerebral ischemia
  • 일반논문[20150601] Effect of Oenanthe Javanica Extract on Antioxidant Enzyme in the Rat Liver
  • 일반논문[20150501] Effect of pioglitazone on excitotoxic neuronal damage in the mouse hippocampus
  • 일반논문[20150301] New expression of 5-HT1A receptor in astrocytes in the gerbil hippocampal CA1 region following transient global cerebral ischemia
  • 일반논문[20150301] Change of calbindin D-28k protein expression in the mice hippocampus after lipopolysaccharide treatment
  • 일반논문[20150201] Ischemic preconditioning protects hippocampal pyramidal neurons from transient ischemic injury via the attenuation of oxidative damage through upregulating heme oxygenase-1
  • 일반논문[20150101] Impact of hyperthermia before and during ischemia-reperfusion on neuronal damage and gliosis in the gerbil hippocampus induced by transient cerebral ischemia
  • 일반논문[20141201] Effects of High-Fat Diet on Neuronal Damage, Gliosis, Inflammatory Process and Oxidative Stress in the Hippocampus Induced by Transient Cerebral Ischemia
  • 일반논문[20141001] Neuroprotection via maintenance or increase of antioxidants and neurotrophic factors in ischemic gerbil hippocampus treated with tanshinone I
  • 일반논문[20140915] Changes and expressions of Redd1 in neurons and glial cells in the gerbil hippocampus proper following transient global cerebral ischemia
  • 일반논문[20140901] Comparison of arylalkylamine N-acetyltransferase and melatonin receptor type 1B immunoreactivity between young adult and aged canine spinal cord
  • 일반논문[20140801] Increased Dynamin-1 and -2 Protein Expression in the Aged Gerbil Hippocampus
  • 일반논문[20140701] Anti-inflammatory Effect of Tanshinone I in Neuroprotection Against Cerebral Ischemia-Reperfusion Injury in the Gerbil Hippocampus
  • 일반논문[20140630] Change of peroxisome proliferator-activated receptor γ expression pattern in the gerbil dentate gyrus after transient global cerebral ischemia
  • 일반논문[20140601] Neuroprotection of posttreatment with risperidone, an atypical antipsychotic drug, in rat and gerbil models of ischemic stroke and the maintenance of antioxidants in a gerbil model of ischemic stroke
  • 일반논문[20140401] Decreased Insulin-Like Growth Factor-I and Its Receptor Expression in the Hippocampus and Somatosensory Cortex of the Aged Mouse
  • 일반논문[20140330] Cell proliferation and neuroblast differentiation in the dentate gyrus of high-fat diet-fed mice are increased after rosiglitazone treatment
  • 일반논문[20140215] Differences in neuronal damage and gliosis in the hippocampus between young and adult gerbils induced by long duration of transient cerebral ischemia
  • 일반논문[20131201] Time-course Changes in Immunoreactivities of Glucokinase and Glucokinase Regulatory Protein in the Gerbil Hippocampus Following Transient Cerebral Ischemia
  • 일반논문[20130930] Systemic administration of low dosage of tetanus toxin decreases cell proliferation and neuroblast differentiation in the mouse hippocampal dentate gyrus
  • 일반논문[20130901] Neuroprotective Effect of a New Synthetic Aspirin-decursinol Adduct in Experimental Animal Models of Ischemic Stroke
  • 일반논문[20130501] Decreased Glucokinase Protein Expression in the Aged Gerbil Hippocampus
  • 일반논문[20130201] Neuroprotective effects of Alpinia katsumadai against experimental ischemic damage via control of oxidative stress
  • 일반논문[20130101] Comparison of Alpha-Synuclein Immunoreactivity in the Hippocampus Between the Adult and Aged Beagle Dogs
  • 일반논문[20121101] Comparison of Trophic Factors Changes in the Hippocampal CA1 Region Between the Young and Adult Gerbil Induced by Transient Cerebral Ischemia
  • 일반논문[20121001] Comparison of Glial Activation in the Hippocampal CA1 Region Between The Young and Adult Gerbils After Transient Cerebral Ischemia
  • 일반논문[20121001] Protective Effects of a Novel Synthetic Alpha-Lipoic Acid-Decursinol Hybrid Compound in Experimentally Induced Transient Cerebral Ischemia
  • 일반논문[20120830] Effects of ADHD therapeutic agents, methylphenidate and atomoxetine, on hippocampal neurogenesis in the adolescent mouse dentate gyrus
  • 일반논문[20120715] Neuroprotective effect of fucoidin on lipopolysaccharide accelerated cerebral ischemic injury through inhibition of cytokine expression and neutrophil infiltration
  • 일반논문[20120701] Changes in Ribosomal Protein S3 Immunoreactivity and its Protein Levels in the Gerbil Hippocampus Following Subacute and Chronic Restraint Stress
  • 일반논문[20120601] Comparison of inflammatory cytokines changes in the hippocampal CA1 region between the young and adult gerbil after transient cerebral ischemia
  • 일반논문[20120501] Comparison of the Immunoreactivity of Trx2/Prx3 Redox System in the Hippocampal CA1 Region Between the Young and Adult Gerbil Induced by Transient Cerebral Ischemia
  • 일반논문[20120501] Changes of Ribosomal Protein S3 Immunoreactivity and Its New Expression in Microglia in the Mice Hippocampus After Lipopolysaccharide Treatment
  • 일반논문[20120401] Comparison of Neurogenesis in the Dentate Gyrus Between the Adult and Aged Gerbil Following Transient Global Cerebral Ischemia
  • 일반논문[20120301] Increased Immunoreactivities of Cleaved alpha II-Spectrin and Cleaved Caspase-3 in the Aged Dog Spinal Cord
  • 일반논문[20120301] FoxO3a Changes in Pyramidal Neurons and Expresses in Non-Pyramidal Neurons and Astrocytes in the Gerbil Hippocampal CA1 Region After Transient Cerebral Ischemia
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