박소영 사진

박소영 | 약학대학 약학과

  • 직급:
    부교수

소개

본인은 중앙대학교 약학대학을 졸업한 후 미국 University of Illinois at Chicago
약학대학에서 생약학을 전공으로 박사학위를 취득하였다. 박사학위 과정 중
울금에서 알츠하이머성 치매의 원인물질인 베타-아밀로이드의 독성을
억제하는 컬큐민류를 분리, 구조 결정을 하였으며 그 작용 기전을 세포 수준
에서 규명하였다. 그 후 미국 Northwestern 대학교 의과대학에서 알츠하이머성
치매의 원인을 규명하는 연구를 수행하였다.

본인이 수행하고 있고 또 관심이 있는 연구 분야는 다음과 같다.

1. 알츠하이머성 치매의 치료 및 예방 후보물질 개발: 수명의 연장과 함께 사회
문제로 대두되고 있는 알츠하이머성 치매의 질병 유발 기전 (베타-
아밀로이드와 타우 단백질)을 규명하고 이를 표적으로 하는 치매 예방 또는 치료 천연물 소재를 선별, 그 작용 기전을 세포생물학적 및 분자생물학적 방법으로 규명하여 건강기능식품, 나아가 천연물 신약으로 발전할 수 있는 기초를 마련한다.

2. 웰에이징, 뼈건강 증진 천연물 소재 개발 및 사업화: 노인 인구의 증가와 함께 웰에이징 개념이 중요시되고 있다. 뼈 건강을 증진할 수 있는 천연물 소재, 관절염 등의 염증 억제 천연물 소재를 개발하고 상품화하기 위한 기반을 구축한다.

3. 환경 독성 물질의 치매 유발 상관관계 규명: 공기, 물, 토양, 음식물을 통해
인체에 노출되는 환경 독성 물질들이 치매, 파킨슨병과 같은 퇴행성 뇌질환을
유발하는 상관관계를 규명한다.

학력

  • [1991] 학사 중앙대학교 약학과
  • [2001] 석사 Univ. of Illinois at Chicago College of Pharmacy, Department of Pharma
  • [2001] 박사 Univ. of Illinois at Chicago 약학과 천연물신약 및 기능성소재 개발

주요경력

  • Northwestern University (2003-04-21)

주요연구분야

1. 알츠하이머성 치매 예방 및 치료 천연물 소재 개발
1) 베타-아밀로이드 생성 억제 천연물 소재 개발
2) 베타-아밀로이드 응집 억제 천연물 소재 개발
3) Neuroinflammation 억제 천연물 소재 개발
4) 타우단백질 인산화 억제 천연물 소재 개발
2. 뼈 건강 증진 천연물 소재 개발 및 제품화
3.염증 억제 웰에이징 천연물 소재 개발

컨설팅 가능 분야

1. 천연물 유래 기능성 소재 및 건강기능식품 개발
2. 천연물 유래 신약 개발
3. 활성 천연물 분석법 개발, 대량 생산 및 표준화
4. 유효 물질의 분리 및 구조 동정
5. 활성 천연물 스크리닝법 개발

연구업적

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