정용태 사진

정용태 | 과학기술대학 생명과학부 (자연과학1관)

  • 직급:
    교수

교수소개

고려대학교 생물학과를 졸업하였으며 동 대학원에서 박사 학위를 취득 하였습니다. 박사 학위를 받은 후 미국 국립보건원(NIH, NIAID)에서 박사후 연구원으로 근무 하였습니다. 2003년 부터 단국대 미생물학과에 근무하면서 세포생물학, 바이러스학, 면역학, 종양학등을 학부와 대학원에서 강의하고 있습니다. 레트로바이러스에 관해 연구하고 있으며 특히 (1) 세포내 억제인자의 레트로바이러스 제어기작에 관한 연구, (2) 마우스레트로바이러스를 이용한 합포체 형성 기작에 대한 연구,
(3) 이종간 장기이식시 돼지내인성 바이러스(PERV)의 병인성에 대한 연구등이 중점 연구분야 입니다.

교육철학

가르치면서 배운다는 말이 있다. 먼저 학생들이 수많은 정보로 부터 어떻게 참된 지식을 찾을 수 있는지와 이들 지식을 어떻게 정리할수 있는지 가르친다. 학생들이 다른 학생들을 가르치면서 배울 수 있도록 사회성을 키우고 다른 학생들과 소통할 수 있는 능력을 함양할 수 있도록 도와준다.

학력

  • [1989] 학사 고려대학교 / 생물 / 미생물
  • [1993] 석사 고려대학교 / 생물 / 세균학
  • [1997] 박사 고려대학교 / 생물 / 분자바이러스학

주요경력

  • 고려대학교 (1991-09-01)
  • 고려대학교 (1992-03-02)
  • 고려대학교 (1997-03-02)
  • 가톨릭대학교 의과대학 (1993-03-02)
  • 미국 NIH (1997-09-08)
  • 미국 NIH (1998-05-01)

주요연구분야

(1) 세포내 억제인자의 레트로바이러스 제어기작에 관한 연구
(2) 마우스레트로바이러스를 이용한 합포체 형성 기작에 대한 연구
(3) 이종간 장기이식시 돼지내인성 바이러스(PERV)의 병인성에 대한 연구
(4) 복제가능 레트로 바이러스 벡터 개발에 관한 연구

컨설팅 가능 분야

1. 이종간 장기이식시 돼지내인성 바이러스(PERV)의 병인성
2. 복제가능 레트로 바이러스 벡터 개발

연구업적

  • 연구보고서[20081128] 이종이식관련 돼지 내인성 바이러스(PERV)특성 및 인체 감염성 조사를 통한 안전성 확립(2차년도)
  • 연구보고서[20080130] 돼지 내인성 retrovirus (PERV, Porcine Endogenous Retrovirus) 유래의 새로운 vector system의 개발
  • 연구보고서[20071008] 이종이식관련 돼지 내인성 바이러스 특성 및 인체 감염성 조사를 통한 안전성 확립(1차년도)
  • 연구보고서[20060919] 레트로바이러스 감염에 대한 세포내 저항인자의 작용기작에 대한 연구(2차년)
  • 연구보고서[20040430] 젊은과학자연구활동지원사업연차보고서(레트로바이러스 감염에 대한 세포내 저항인자의 작용기작에 대한 연구)
  • 일반논문[20240228] A Replication-Competent Retroviral Vector Expressing the HERV-W Envelope Glycoprotein is a Potential Tool for Cancer Gene Therapy
  • 일반논문[20220301] Construction of SARS‑CoV‑2 spike‑pseudotyped retroviral vector inducing syncytia formation
  • 일반논문[20220101] Production of a replicating retroviral vector expressing Reovirus fast protein for cancer gene therapy
  • 일반논문[20201201] Semi-replication-competent retroviral vectors expressing gibbon ape leukemia virus fusogenic membrane glycoprotein (GALV FMG) gene for cancer gene therapy
  • 일반논문[20200601] Reactive-oxygen-species-mediated mechanism for photoinduced antibacterial and antiviral activities of Ag3PO4
  • 일반논문[20200501] Construction of a replication-competent retroviral vector for expression of the VSV-G envelope glycoprotein for cancer gene therapy
  • 일반논문[20190301] Construction of replication-competent oncolytic retroviral vectors expressing R peptide-truncated 10A1 envelope glycoprotein
  • 일반논문[20180701] Human-APOBEC3G-dependent restriction of porcine endogenous retrovirus replication is mediated by cytidine deamination and inhibition of DNA strand transfer during reverse transcription
  • 일반논문[20170501] Expression of bovine rotavirus VP8 and preparation of IgY antibodies against recombinant VP8
  • 일반논문[20161201] Mouse tetherin enhances moloney murine leukemia virus-induced syncytium formation
  • 일반논문[20161201] Development of Serological Procedures for Sensitive, Rapid Detection of Cucumber Mosaic Virus in Lilium
  • 일반논문[20160301] An egg yolk immunoglobulin (RVP6-IgY) specific for a constructed rotavirus VP6 antigen (rVP6)inhibited rotavirus replication in vitro
  • 일반논문[20150801] Differential sensitivity of porcine endogenous retrovirus to APOBEC3-mediated inhibition
  • 일반논문[20140831] Expression of Lily Mottle Virus Coat Protein Gene and Preparation of IgY Antibody against the Recombinant Coat Protein
  • 일반논문[20140601] Use of IgY antibody to recombinant avian reovirus σC protein in the virus diagnostics
  • 일반논문[20140430] A Comparison of the Effects of Retroviral Restriction Factors Involved in Resistance to Porcine Endogenous Retrovirus
  • 일반논문[20140301] Tetherins of various species inhibit the release of porcine endogenous retrovirus from human cells
  • 일반논문[20121231] Development of an Indirect ELISA and Immunocapture RT-PCR for Lily
  • 일반논문[20120211] Characterization of molecular clones of porcine endogenous retrovirus-Acontaining different numbers of U3 repeat boxes in the long terminal repeat region
  • 일반논문[20110430] Evaluation of the Potential Risk of Porcine Endogenous Retrovirus (PERV) Infection in Nude Mice
  • 일반논문[20110101] The rapid production of high-titer porcine endogenous retrovirus(PERV)-B env pseudotype and construction of an EGFP-expressing replication competent PERV-A vector
  • 일반논문[20101231] Development of a real time RT-PCR with SYBR Green dye for the detection of several viruses from the bulbs and leaves of lily
  • 일반논문[20100330] C형 돼지 내인성 레트로바이러스(PERV)의 C-말단 외막당단백질에 의한 재조합 PERV-A/C의 감염력 조절
  • 일반논문[20090930] 합포체 분석을 위해 R 펩타이드가 결여된 형광 표지 Moloney 마우스레트로바이러스 Molecular Clone 제조
  • 일반논문[20090930] RT-PCR법을 이용한 백합 바이러스 LSV, LMoV, CMV의 검출
  • 일반논문[20081030] Isolation and characterization of PERV-C env from domestic pig in Korea
  • 일반논문[20080428] Generation and characterization of a stable full-length ecotropic murine leukemia virus molecular clone that produces novel phenotypes to Fv1 restriction
  • 일반논문[20080110] Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses
  • 일반논문[20061231] 국내돼지에 존재하는 돼지 내인성 레트로바이러스 외막 단백질 분포양상 분석
  • 일반논문[20060930] 마우스레트로바이러스에 의한 합포체 형성기작 분석
  • 일반논문[20060831] Role of a third extracellular domains of ecotropic receptor in Moloney murine leukemia virus infection
  • 일반논문[20051001] Inducible Vesicular Stomatitis Virus(VSV)L Cell Line for Packaging Recombinant VSV
  • 일반논문[20041230] Characteristics og HIV-Tat protein transduction domain
  • 일반논문[20041130] Novel host range and cytopathic variant of ecotropic friend murine leukemia virus
  • 일반논문[20040531] Inhibition of Herpesvirus-6B RNA replication by short interference RNAs
  • 일반논문[20031231] 에어컨내 세균의 분리, 동정 및 위생
  • 일반논문[20031231] Phylogenetic Analysis of Phenanthrene-Degrading Sphingomonas
  • 일반논문[20031231] 1998년-2002년 서울 강남성모병원에 내원한 환자혈청에서 한탄바이러스 감염에 대한 혈청 역학적 조사
  • 일반논문[20031201] Characterization of Recombinant Nonecotropic Murine Leukemia Viruses from the Wild Mouse Species Mus spretus.
  • 일반논문[20030530] Generation of Novel Syncytium-Inducing and Host Range Variants of Ecotropic Moloney Murine Leukemia Virus in Mus spicilegus
  • 저서/역서[20200310] (Brock의) 미생물학
  • 저서/역서[20200310] (Brock의) 핵심미생물학
  • 저서/역서[20110228] Black의 미생물학
  • 저서/역서[20090225] 생명과학 개론(Concepts in Biology)
  • 저서/역서[20070228] 의학미생물학
  • 학술발표[20180716] Development of gammaretroviral vectors encoding the truncated amphotropic envelope for cancer gene therapy
  • 학술발표[20171102] Prokaryotic Expression of VP1 Genes of Duck Hepatitis A Virus Type 1 (DHAV-1) and Type 3 (DHAV-3)
  • 학술발표[20170825] Construction of amphotropic retroviral replicating vector encoding codon optimized yeast cytosine deaminase
  • 학술발표[20161103] Production of egg yolk immunoglobulin against the intracellular salmonid pathogen Pscirickettsiosis salmonis
  • 학술발표[20160919] Expression of infectious pancreatic necrosis virus (IPNV) VP2 and preparation of IgY antibodies against recombinant VP2
  • 학술발표[20160826] Development of gammaretroviral vectors for gene thansfer
  • 학술발표[20151105] Construction of an EGFP-expressing replication competent porcine circovirus type 2
  • 학술발표[20150829] Dual inhibitory effects of APOBEC3G on replication of porcine endogenous retrovirus
  • 학술발표[20150608] DEAMINASE ACTIVITY OF APOBEC3 IS REQUIRED FOR EFFICIENT RESTRICTION OF PORCINE ENDOGENOUS RETROVIRUS
  • 학술발표[20141030] Deaminase-independent inhibition of PERV reverse transcription by APOBEC3G
  • 학술발표[20140821] Mouse tetherin enhances MLV-induced syncytium formation
  • 학술발표[20140623] Differential Sensitivity of Porcine Endogenous Retrovirus to APOBEC3-Mediated Inhibition
  • 학술발표[20131017] Expression of Porcine Circovirus Type 2 Capsid Protein and Preparation of IgY Antibody against Recombinant Capsid Protein
  • 학술발표[20130823] Development of retroviral vectors for gene transfer
  • 학술발표[20130724] Tetherins of various species inhibit the release of porcine endogenous retrovirus from human cells
  • 학술발표[20130524] Expression of Lily mottle virus coat protein gene and preparation of IgY antibodies against recombinant coat protein
  • 학술발표[20121012] Expression of recombinant fowl adenovirus fiber 2 fragment gene and its production of specific antibody in laying hen
  • 학술발표[20120817] Comparison of the effects of retroviral restriction factors involved in resistance to retrovirus
  • 학술발표[20120723] Comparison of the Effects of Retroviral Restriction Factors Involved in Resistance to Porcine Eendogenous Retrovirus
  • 학술발표[20120627] Expression of bovine rotavirus VP8 and preparation of IgY antibodies against recombinant VP8
  • 학술발표[20120518] Development of Serological Procedures for Sensitive and Rapid Detection of Cucumber Mosaic Virus in Lilium
  • 학술발표[20120328] Molecular variability of lily virus isolates from Korea
  • 학술발표[20111028] Development of an ID-ELISA and immunocapture RT-PCR for Lily viruses detection
  • 학술발표[20111013] Comparison of the effects of retroviral restriction factors involved in resistance to amphotropic murine leukemia virus
  • 학술발표[20110627] Characterization of milecular clone of PERV-A containing a different number of U3 repeat box in the long terminal repeat region
  • 학술발표[20101022] Detection of lily viruses by multiplex RT-PCR and quantification by TaqMan real-time RT-PCR
  • 학술발표[20101015] Construction of an EGFP-expressing replication competent PERV-A vector
  • 학술발표[20091023] Evaluation of the potential risk of pocine endogenous retrovirus (PERV) infection in vivo after xenotransplantation
  • 학술발표[20090713] GFP-tagged retroviral envelope protein for analysis of syncytium by R peptide
  • 학술발표[20090529] SYBR Green I-based Real Time RT-PCR for the Quantitative Detection of Lily Viruses from Leaves or Lily Bulbs
  • 학술발표[20090523] Detection of Lily mottle virus, Lily symptomless virus and Cucumber mosaic virus in Lillium by RT-PCR
  • 학술발표[20081016] Use of a fluorescently labelled MLVs for studying the Fv1-mediated mechanism of resistance to retroviral infection
  • 학술발표[20080712] Isolation and characterization of PERV-C env from the domestic pig in Korea
  • 학술발표[20071011] Rapid Production of High Titer Retrovirus/PERV-B env Pseudotype
  • 학술발표[20070426] Construction of an infectious replication-competent molecular clone of ecotropic porcine endogenous retrovirus class C
  • 학술발표[20061020] Analysis of Syncytium Formation Mechanism induced by Ecotropic Murine Retrovirus
  • 학술발표[20061020] Characterization of a third extracellular domains of ecotropic receptor in Moloney murine leukemia virus infection
  • 학술발표[20051013] Construction and characterization of a stable full-length ecotropic mulv molecular clone for studying the genetic determinant of Fv1 restriction
  • 학술발표[20051013] Role of receptor polymorphism in syncytium induction by ecotropic mouse gammaretrovirus
  • 학술발표[20041021] A novel host range and cytopathic variant of ecotropic friend murine leukemia virus
캠퍼스별 교무팀