서동완 사진

서동완 | 약학대학 약학과 (약학관)

  • 직급:
    교수

학력

  • [1993] 학사 성균관대학교(자연과학캠퍼스) / 약학과
  • [1995] 석사 성균관대학교(자연과학캠퍼스) / 약학과 / 생화학
  • [2000] 박사 성균관대학교(자연과학캠퍼스) / 약학과 / 생화학

주요경력

  • 미국립보건원 암연구소 (2000-04-19)
  • 강원대학교 의생명과학대학 (2006-03-01)

주요연구분야

1. TIMP-2의 혈관신생 및 암전이 제어기전 연구
2. 혈관신생 관련 질환 개선 기능성 소재 및 치료제 개발 연구

연구업적

  • 일반논문[20231201] Prediction of skin sensitization using machine learning
  • 일반논문[20231026] The effect of compression pressure on the first layer surface roughness and delamination of metformin and evogliptin bilayer and trilayer tablets
  • 일반논문[20221201] A novel telomerase-derived peptide GV1001-mediated inhibition of angiogenesis: Regulation of VEGF/VEGFR-2 signaling pathways
  • 일반논문[20220401] Spiraea prunifolia leaves extract inhibits adipogenesis and lipogenesis by promoting beta-oxidation in high fat diet-induced obese mice
  • 일반논문[20220201] Broussonin A- and B-mediated inhibition of angiogenesis by blockade of VEGFR-2 signalling pathways and integrin beta 1 expression
  • 일반논문[20220101] Tetracera loureiri extract regulates lipopolysaccharide-induced inflammatory response via nuclear factor-B and mitogen activated protein kinase signaling pathways
  • 일반논문[20210301] Improvement of Obesity and Dyslipidemic Activity of Amomum tsao-ko in C57BL/6 Mice Fed a High-Carbohydrate Diet
  • 일반논문[20201001] A novel role for alpha-viniferin in suppressing angiogenesis by blocking the VEGFR-2/p70(S6K) signaling pathway
  • 일반논문[20200601] Effects of anti-wrinkle and skin-whitening fermented black ginseng on human subjects and underlying mechanism of action
  • 일반논문[20200501] Ginsenoside Rb1 and Rb2 upregulate Akt/mTOR signaling-mediated muscular hypertrophy and myoblast differentiation
  • 일반논문[20200401] Combretum quadrangulare extract attenuates atopic dermatitis-like skin lesions through modulation of MAPK signaling in balb/c mice
  • 일반논문[20200201] Novel functions for 2-phenylbenzimidazole-5-sulphonic acid: Inhibition of ovarian cancer cell responses and tumour angiogenesis
  • 일반논문[20190401] Risk assessment of triclosan, a cosmetic preservative
  • 일반논문[20180101] T-cell immune regulator 1 enhances metastasis in hepatocellular carcinoma
  • 일반논문[20180101] Black ginseng activates Akt signaling, thereby enhancing myoblast differentiation and myotube growth
  • 일반논문[20171101] An isoflavone compound daidzein elicits myoblast differentiation and myotube growth
  • 일반논문[20171001] Trigonostemon reidioides modulates endothelial cell proliferation, migration and tube formation via down-regulation of the Akt signaling pathways
  • 일반논문[20171001] Ginsenoside Rg1 from Panax ginseng enhances myoblast differentiation and myotube growth
  • 일반논문[20170401] Epicatechin elicits MyoD-dependent myoblast differentiation and myogenic conversion of fibroblasts
  • 일반논문[20170101] Marmesin-mediated suppression of VEGF/VEGFR and integrin β1 expression: Its implication in non-small cell lung cancer cell responses and tumor angiogenesis
  • 일반논문[20161101] Validation of method determining marmesin in Broussonetia kazinoki extract
  • 일반논문[20161001] Dehydrocorydaline promotes myogenic differentiation via p38 MAPK activation
  • 일반논문[20161001] PKN2 and Cdo interact to activate AKT and promote myoblast differentiation
  • 일반논문[20160501] 5-Caffeoylquinic acid inhibits invasion of non-small cell lung cancer cells through the inactivation of p70S6K and Akt activity: Involvement of p53 in differential regulation of signaling pathways
  • 일반논문[20160301] Bakuchiol augments MyoD activation leading to enhanced myoblast differentiation
  • 일반논문[20160201] 10-Gingerol inhibits proliferation and invasion of MDA-MB-231 breast cancer cells through suppression of Akt and p38MAPK activity
  • 일반논문[20160101] Peroxisome proliferator-activated receptor beta/delta(PPARbeta/delta) activates promyogenic signaling pathways, thereby promoting myoblast differentiation
  • 일반논문[20151201] Marmesin is a novel angiogenesis inhibitor: Regulatory effect and molecular mechanism on endothelial cell fate and angiogenesis
  • 일반논문[20150901] Syntaxin 4 regulates the surface localization of a promyogenic receptor Cdo thereby promoting myogenic differentiation
  • 일반논문[20150701] Ligularia fischeri inhibits endothelial cell proliferation, invasion and tube formation through the inactivation of mitogenic signaling pathways and regulation of vascular endothelial cadherin distribution and matrix metalloproteinase expression
  • 일반논문[20150201] Anti-angiogenic effects of Siegesbeckia glabrescens are mediated by suppression of the Akt and p70S6K-dependent signaling pathways
  • 일반논문[20150102] Kazinol-P from Broussonetia kazinoki enhances skeletal muscle differentiation via p38MAPK and MyoD
  • 일반논문[20141201] Tetrahydropalmatine promotes myoblast differentiation through activation of p38MAPK and MyoD
  • 일반논문[20141201] Neolignan inhibitors of antigen-induced degranulation in RBL-2H3 cells from the needles of Pinus thunbergii
  • 일반논문[20141001] Broussonetia kazinoki modulates the expression of VEGFR-2 and MMP-2 through the inhibition of ERK, Akt and p70S6K-dependent signaling pathways: its implication in endothelial cell proliferation, migration and tubular formation
  • 일반논문[20140805] A mechanistic study on the anti-cancer activity of ethyl caffeate in human ovarian cancer SKOV-3 cells
  • 일반논문[20140301] Regulatory effects of Siegesbeckia glabrescens on non-small cell lung cancer cell proliferation and invasion
  • 일반논문[20140228] TIMP-2-derived 18-mer peptide inhibits endothelial cell proliferation and migration through cAMP/PKA-dependent mechanism
  • 일반논문[20131201] Phytochemical linarin enriched in the flower of Chrysanthemum indicum inhibits proliferation of A549 human alveolar basal epithelial cells through suppression of Akt-dependent signaling pathway
  • 일반논문[20131201] Ligularia fischeri regulates lung cancer cell proliferation and migration through down-regulation of epidermal growth factor receptor and integrin beta1 expression
  • 일반논문[20131020] Phenolic amides from the fruits of Tribulus terrestris and their inhibitory effects on the production of nitric oxide
  • 일반논문[20130724] Two new furostanol glycosides from the fruits of Tribulus terrestris
  • 일반논문[20130701] The in vitro anti-tumor activity of Siegesbeckia glabrescens against ovarian cancer through suppression of receptor tyrosine kinase expression and their signaling pathways
  • 일반논문[20130601] Enzymatic production and expression of shRNAmir30 from cDNAs
  • 일반논문[20130301] PRMT6 overexpression upregulates TSP-1 and downregulates MMPs: its implication in motility and invasion
  • 일반논문[20130201] Knockdown of integrin alpha3beta1 expression induces proliferation and migration of non-small cell lung cancer cells
  • 일반논문[20121207] Antagonism of VEGF-A-induced increase in vascular permeability by an integrin alpha3beta1-Shp-1-cAMP/PKA pathway
  • 일반논문[20120501] 1 beta-Hydroxy-2-oxopomolic Acid Isolated from Agrimonia pilosa Extract Inhibits Adipogenesis in 3T3-L1 Cells
  • 지식재산권[20190516] 브루소닌 A 및 B를 유효성분으로 함유하는 혈관신생 억제용 조성물
  • 지식재산권[20171107] 마메신을 유효성분으로 함유하는 혈관신생 억제용 조성물
  • 지식재산권[20170102] 닥나무 추출물을 유효성분으로 함유하는 혈관신생 억제용 조성물(Composition for inhibiting angiogenesis comprising Broussonetia kazinoki extract)
  • 지식재산권[20160316] 닥나무 추출물을 유효성분으로 함유하는 당뇨합병증의 예방 및 치료용 조성물
  • 지식재산권[20130130] 재조합 대장균을 이용한 세피아프테린의 제조방법(Method for production of sepiapterin with recombinant E. coli)
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