논문 발표 실적

2025년

Effects of Exposure of PHMG-p, a Humidifier Disinfectant Component, on Eye Dryness: A Study on a Rat Model Based on 1H-NMR Metabolomics. International Journal of Molecular Sciences, 26(6)
HepatoToxicity Portal (HTP): an integrated database of drug-induced hepatotoxicity knowledgebase and graph neural network-based prediction model. Journal of Cheminformatics, 17(7)
Metabolomics approach to physiological adaptive mechanisms in repetitive confined-water scuba diving under mild hyperoxia using 1H-NMR. Eur J Appl Physiol
Mass spectrometry (MS)-based metabolomics of plasma and urine in dry eye disease (DED)-induced rat model. TAYLOR & FRANCIS INC, 88(8): 122-135

2024년

Reduction in integrin α3β1 modulates lung cancer motility and invasion through p70S6K-dependent E-cadherin localization. CELLULAR AND MOLECULAR BIOLOGY, 70(7): 115-121
Identification of acrolein as a novel diagnostic odor biomarker for 1,2,3-trichloropropane-induced hepatotoxicity in Sprague Dawley rats. Toxicological Research, 40(12): 639-651
Licochalcone A attenuates NMDA-induced neurotoxicity. Anim Cells Syst (Seoul) 28(1):392-400
Repeated-dose toxicity and toxicokinetic study of isobutylparaben in rats subcutaneously treated for 13 weeks. Archives of Toxicology 98(7):2231-2246
Mass spectrometry (MS)-based metabolomics of plasma and urine in dry eye disease (DED)-induced rat model. J Toxicol Environ Health A, 88(3):122-135
Risk assessment of cyclohexasiloxane D6 in cosmetic products. Toxicological Research, 40(13): 421-429
Safety assessment of cocamidopropyl betaine, a cosmetic ingredient. Toxicological Research, 40(11): 361-375
Analytical method development and dermal absorption of gallic acid, a hair dye ingredient. Toxicological Research, 40(5): 449-456

2023년

Prediction of skin sensitization using machine learning.. Toxicology in vitro 93:105690
Analytical method development and dermal absorption of 2-amino-5-nitrophenol (2A5NP), a hair dye ingredient under oxidative condition.. Toxicological Research 39: 231-238
Development of an LC–MS/MS Assay and Toxicokinetic Characterization of Hexamethylenetetramine in Rats.. Toxics 11: 337
Negligible Toxicokinetic Differences of Glyphosate by Different Vehicles in Rats.. Toxics 11: 67

2022년

Urinary Metabolomics in Young Soccer Players after Winter Training Season.. Metabolites 12: 1283
Current trends in read-across applications for chemical risk assessments and chemical registrations in the Republic of Korea.. Journal of Toxicology and Environmental Health, Part B-Critical Reviews 25: 393-404
Toxicokinetics, Percutaneous Absorption and Tissue Distribution of Benzophenone‐3, an UV Filtering Agent, in Rats.. Toxics 10: 672
Analytical Method Development and Dermal Absorption of Pyrogallol, a Hair Dye Ingredient.. Toxics 10: 570
A Metabolomics Approach to Sulforaphane Efficacy in Secondhand Smoking-Induced Pulmonary Damage in Mice.. Metabolites 12: 518
Pharmacokinetics and the Dermal Absorption of Bromochlorophene, a Cosmetic Preservative Ingredient, in Rats.. Toxics 10: 329
Prenatal developmental toxicity study of 2,4-dichlorobenzyl alcohol in rats.. Regulatory Toxicology and Pharmacology 132:105168
Microfluidic system with light intensity filters facilitating the application of photodynamic therapy for high-throughput drug screening.. Photodiagnosis and Photodynamic Therapy 38:102812
Metabolomics profiling of valproic acid-induced symptoms resembling autism spectrum disorders using 1H NMR spectral analysis in rat model.. Journal of Toxicology and Environmental Health, part A 85:1-13
Using intracellular metabolic profiling to identify novel biomarkers of cisplatin-induced acute kidney injury in NRK-52E cells.. Journal of Toxicology and Environmental Health, part A 85:29-42

2021년

Effects of tobacco compound 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) on the expression of epigenetically regulated genes in lung carcinogenesis.. Journal of Toxicology and Environmental Health, part A 84:1004-1019
Validation of Quantitative Structure-Activity Relationship (QSAR) and Quantitative Structure-Property Relationship (QSPR) approaches as alternatives to skin sensitization risk assessment.. Journal of Toxicology and Environmental Health, part A 84:945-959
Topical application of celastrol alleviates atopic dermatitis symptoms mediated through the regulation of thymic stromal lymphopoietin and group 2 innate lymphoid cells.. Journal of Toxicology and Environmental Health, part A 84:922-931
Exposure to long-term evolution radiofrequency electromagnetic fields decreases neuroblastoma cell proliferation via Akt/mTOR-mediated cellular senescence.. Journal of Toxicology and Environmental Health, part A 84:846-857
Analytical method development and percutaneous absorption of propylidene phthalide, a cosmetic ingredient.. Journal of Toxicology and Environmental Health, part A 84:811-820
Thirteen-week subcutaneous repeated dose toxicity study of butylparaben and its toxicokinetics in rats.. Archives of Toxicology 95:2037-2050
Current opinion on risk assessment of cosmetics.. Journal of Toxicology and Environmental Health, part B 24:137-161
Effects of application amounts on in vitro dermal absorption test using caffeine and testosterone.. Pharmaceutics 13:641
Metabolomics approach to biomarkers of dry eye disease using 1H-NMR in rats.. Journal of Toxicology and Environmental Health, part A 84:313-330

2020년

Risk assessment of unintentional phthalates contaminants in cosmetics.. Regulatory Toxicology and Pharmacology 115:104687
Effects of anti-wrinkle and skin-whitening fermented balck ginseng on humansubjects and underlying mechanism of action.. Journal of Toxicology and Environmental Health, part A 83:423-437
Integration of transcriptomics, proteomics and metabolomics identifies biomarkers for pulmonary injury by polyhexamethylene guanidine phosphate (PHMG-p), a humidifier disinfectant, in rats.. Archives of Toxicology 94:887-909
Para-phenylenediamine, an oxidative hair dye ingredient, increases thymic stromal lymphopoietin and proinflammatory cytokines causing acute dermatitis.. Toxicological Research 36:329-336
Novel functions for 2-phenylbenzylimidazole-5-sulphonic acid: Inhibition of ovarian cancer cell responses and tumor angiogenesis.. Journal of Cellular and Molecular Medicine 24:2688-2700

2019년

Estrogen deficiency potentiates thioacetamide-induced hepatic fibrosis in Sprague-Dawley rats.. International Journal of Molecular Sciences 20:3709
Metabolomics approach to serum biomarker for laxative effects of red Liriope platyphylla in loperamide-induced constipation of SD rats.. Laboratory Animal Research 35:9
Risk assessment of volatile organic compounds (VOCs) detected in sanitary pads.. Journal of Toxicology and Environmental Health, part A 82:678-695
The relationship between epidermiology factors and usage pattern of hair care products in Korea.. Annals of Dermatology 31:307-314
Quantitative structure–activity and quantitative structure–property relationship approaches as alternative skin sensitization risk assessment methods.. Journal of Toxicology and Environmental Health, part A 82:447-472
Possible effects of radiofrequency electromagnetic field exposure on central nerve system.. Biomolecules & Therapeutics 27:265-275
Alternative skin sensitization prediction and risk assessment using proinflammatory biomarkers, interleukin-1 beta (IL-1β) and inducible nitric oxide synthase (iNOS).. Journal of Toxicology and Environmental Health, part A 82:361-378
Risk assessment of triclosan, a cosmetic preservative.. Toxicological Research 35:137-154
Risk assessment of ethylhexyl dimethyl PABA in cosmetics.. Toxicological Research 35:131-136.
Risk assessment of drometrizole, a cosmetic ingredient used as an ultraviolet light absorber.. Toxicological Research 35:119-129
Risk assessment of 5-chloro-2-methylisothiazol-3(2H)-one/2-methylisothiazol-3(2H)-one (CMIT/MIT) used as a preservative in cosmetics.. Toxicological Research 35:103-117
Effect of combined exposure to EDTA and zinc pyrithione on pyrithione absorption in rats.. Toxicological Research 35:155-160
Percutaneous permeability of 1-phenoxy-2-propanol, a preservative in cosmetics.. Regulatory Toxicology and Pharmacology 103:56-62
Perspectives on trace chemical safety and chemophobia: risk communication and risk management.. Journal of Toxicology and Environmental Health, part A 82:186-199
The relationship between epidermiology factors and usage pattern of hair care products in Korea.. Annals of Dermatology 31:307-314
1H NMR toxicometabolomics following cisplatin-induced nephrotoxicity in male rats.. The Journal of Toxicological Sciences 44:57-71

2018년

Serum and urine toxicometabolomics following gentamicin-induced nephrotoxicity in male Sprague-Dawley rats.. Journal of Toxicology and Environmental Health, part A 81:408-420
Non-cancer, cancer, and dermal sensitization risk assessment of heavy metals in cosmetics.. Journal of Toxicology and Environmental Health, part A 81:432-452
Risk assessment of N-nitrosodiethylamine (NDEA) and N-nitrosodiethanolamine (NDELA) in cosmetics.. Journal of Toxicology and Environmental Health, part A 81:465-480
Analytical method development of methylisothiazolinone, a preservative, in rat plasma using LC-MS/MS.. Journal of Chromatography B Analyt Technol Biomed Life Sci 1100-1101:27-32
Determination of fragrance allergens and their dermal sensitization quantitative risk assessment (QRA) in 107 spray perfumes.. Journal of Toxicology and Environmental Health, part A 81:1173-1185
Effects of several cosmetic preservatives on ros-dependent apoptosis of rat neural progenitor cells.. Biomolecules & Therapeutics 26:608-615
Efficient transdermal delivery of DNA nanostructures alleviates atopic dermatitis symptoms in NC/Nga mice.. Advanced Functional Matrials 28:1801918
Reversed-phase high-performance liquid chromatographic method for the determination of permaton Red (D&C Red No.36) in cosmetics.. Bulletin Of The Korean Chemical Society 39:1219-1222
Phloxine O, a cosmetic colorant, suppresses the expression of thymic stromal lymphopoietin and acute dermatitis symptoms in mice.. Biomolecules & Therapeutics 26:481-486
Metabolic profiling of eccentric exercise-induced muscle damage in human urine.. Toxicological Research 34:199-210
IL-1 and IL-1 as alternative biomarkers for risk assessment and the prediction of skin sensitization potency.. Journal of Toxicology and Environmental Health, part A 81:830-432

2017년

Risk assessment of zinc oxide, a cosmetic ingredient used as a UV filter of sunscreens.. Journal of Toxicology and Environmental Health, part B 20(3):155-182
Analysis of metabolomic patterns in thoroughbreds before and after exercise.. Asian-Australasian Journal of Animal Sciences 30:1633-1642
Assessment of exposure for baby cosmetic care products in a Korean population.. Food and Chemical Toxicology 106:107-113
Integration of traditional and metabolomics biomarkers identifies prognostic metabolites for predicting responsiveness to nutritional intervention against oxidative stress and inflammation.. Nutrients 9(3): 233
Anti‑wrinkle effect of fermented black ginseng on human fibroblasts.. International Journal of Molecular Medicine 39:681-686

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